TEMECULA, Calif., April 9, 2007-- CVAC™ Systems, Inc. and researchers from Stanford University and the VA Palo Alto Health Care System (VAPAHCS) have entered into a new agreement to expand research to include the effect of the Cyclic Variations in Altitude Conditioning (CVAC ) process in middle-aged men. The study is currently recruiting subjects and is expected to commence the second week of April 2007. A second CVAC system will be supplied to the VAPAHCS as part of the agreement.

The principal investigator of the study is Anne L. Friedlander, PhD., Director of the Exercise Physiology Lab in the Clinical Studies Unit at the VAPAHCS and a Consulting Professor for the Program in Human Biology at Stanford University. Dr. Friedlander comments, “This 8- week protocol is designed to measure a wide variety of outcomes including cholesterol profiles and hormones, such as testosterone, to determine if the CVAC™ process can significantly reduce the risk factors of diseases associated with the metabolic syndrome and aging. This is an exciting area of research that, if proven to be effective, could have a profound impact on health, quality of life and longevity.”

“This new area of research into the natural steroidogenic effects of the CVAC process is especially important because recent data from a study of 950 men in the “Massachusetts Male Aging Study,” published in the March 2006 Journal of Clinical Endocrinology & Metabolism, links low total testosterone levels to the development of metabolic syndrome. Moreover, the “Rancho Bernardo Study” of 294 men, published in 2002 by the American Diabetes Association in Diabetes Care, links low total testosterone to the development of type 2 diabetes and insulin resistance. Also, the March 2006 issue of the Journal of the American Medical Association contains a systematic review and meta-analysis in which Harvard Medical School researchers concluded that high testosterone levels are associated with a lower risk of the development of type 2 diabetes in men,” commented Allen Ruszkowski, President and CEO of CVAC Systems, Inc.

About VAPAHCS
VAPAHCS is a teaching hospital, providing a full range of patient care services, with state-of-the-art technology as well as education and research. VAPAHCS maintains one of the top three research programs in the VA. An Affiliation with the Stanford University School of Medicine provides a rich academic environment including medical training for physicians in virtually all specialties and subspecialties.

About CVAC Systems, Inc.
CVAC Systems, Inc., headquartered in Temecula, Calif., is privately funded and is seeking to place CVAC systems at key luminary research sites for the development of several patent-pending applications such as performance enhancement, disease prevention, therapy and advanced health. For these plans, the Company is seeking a first-round venture/institutional financing.

Stanford407 (PDF)

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Please note: The information contained within this document is intended for prospective researchers only, and is not intended for patients or health care providers. Any references to therapeutic applications are for discussion and research purposes only.